The principal goal of Theodosius Dobzhansky Center for Genome BioInformatics is to build a community where genetic and computer scientists, students, fellows and staff labor to develop, test, and apply innovative computational routines for human gene discovery, for vertebrate genome assembly and annotation, for functional imputation and for translation to global heath and environmental well being.
Our strategy is to develop and implement fast, proven, efficient, computational algorithms for genome assembly, annotation, interpretation, gene discovery and genome mining.
Our hope would be to empower one day soon all available vertebrate species with a genomic resolution for study, and application for comparative medicine as well as species betterment and conservation.
The bedrock for these efforts is to embrace and improve the phenomenal advances of genome bio-technology, sequence databases and analytical routines to resolve the most important lessons of 400 million years of vertebrate adaptive evolution for comparative biology (physiology, biochemistry, endocrinology, development, neuroscience and others) and particularly comparative medicine. These discoveries invariably have applications in human or animal improvement.
We propose to accomplish these goals by active facilitation of international science expertise, access and cooperation to build accessible informatics tools for gene discovery, gene transfer, gene therapy and imputation for drug development.